All charts and data below are CPI-U inflation-adjusted and with dividends reinvested. (Why?)
XBI real return snapshot: after CPI-U inflation, XBI returned +78.94% over the past year and +22.99% YTD, with dividends reinvested. Since Feb. 6, 2006, XBI is up +491.17% in real purchasing-power return, or +9.11%/yr, and is currently −29.93% below its real total-return high on Feb. 8, 2021.
Data ending Fri Jun. 26, 2026
| Mon 2006-02-06💬 to Fri 2026-06-26 |
YTD
Return |
1 Year
Return |
||||
|---|---|---|---|---|---|---|
| XBI × |
+22.99%
2026-06-26 |
+78.94%
2026-06-26 |
||||
| SPDR S&P Biotech ETF Exchange-Traded Fund | ||||||
| Mon 2006-02-06💬 to Fri 2026-06-26 |
Overall
Return |
Exponential
Trendline |
||||
|---|---|---|---|---|---|---|
| XBI × |
+491.17%
+9.11%/yr |
+9.82%/yr
(R2=0.756) |
||||
| SPDR S&P Biotech ETF Exchange-Traded Fund | ||||||
| Mon 2006-02-06💬 to Fri 2026-06-26 |
Start
Value |
End
Value |
||||
|---|---|---|---|---|---|---|
| XBI × |
$10,000.00
2006-02-06 |
$59,117.41
2026-06-26 |
||||
| SPDR S&P Biotech ETF Exchange-Traded Fund | ||||||
| Year | XBI |
|---|---|
| 2026 (YTD) | +22.99% |
| 2025 | +32.35% |
| 2024 | −1.82% |
| 2023 | +4.11% |
| 2022 | −30.37% |
| 2021 | −25.68% |
| 2020 | +46.34% |
| 2019 | +29.60% |
| 2018 | −16.86% |
| 2017 | +40.80% |
| 2016 | −17.16% |
| 2015 | +12.75% |
| 2014 | +43.89% |
| 2013 | +46.19% |
| 2012 | +30.43% |
| 2011 | +2.23% |
| 2010 | +15.87% |
| 2009 | −2.30% |
| 2008 | −8.65% |
| 2007 | +23.96% |
| 2006 | −7.89% |
| Mon 2006-02-06💬 to Fri 2026-06-26 |
Current
Drawdown |
Worst
Drawdown |
||||
|---|---|---|---|---|---|---|
| XBI × |
−29.93%
from 2021-02-08 peak |
−68.61%
2023-10-27 from 2021-02-08 peak |
||||
| SPDR S&P Biotech ETF Exchange-Traded Fund | ||||||
| Period ending Fri 2026-06-26 |
1
Year |
2
Years |
3
Years |
5
Years |
10
Years |
|
|---|---|---|---|---|---|---|
| XBI × | +78.94% |
+58.32% +25.82%/yr |
+70.60% +19.49%/yr |
−8.99% −1.87%/yr |
+117.87% +8.10%/yr |
|
| SPDR S&P Biotech ETF Exchange-Traded Fund | ||||||
