All charts and data below are with dividends reinvested. (Inflation adjustment is OFF !)
XBI total return snapshot: XBI returned +65.22% over the past year and +26.57% YTD, with dividends reinvested. Since Feb. 6, 2006, XBI is up +893.77% in nominal total return, or +11.79%/yr, and is currently −10.80% below its total-return high on Feb. 8, 2021.
Data ending Wed Sep. 16, 2026
| Mon 2006-02-06💬 to Wed 2026-09-16 |
Overall
Return |
Exponential
Trendline |
||||
|---|---|---|---|---|---|---|
| XBI × |
+893.77%
+11.79%/yr |
+12.37%/yr
R2=0.856 |
||||
| SPDR S&P Biotech ETF Exchange-Traded Fund | ||||||
| Mon 2006-02-06💬 to Wed 2026-09-16 |
Start
Value |
End
Value |
|---|---|---|
| XBI × |
$10,000.00
2006-02-06 |
$99,376.72
2026-09-16 |
| YTD | YoY | |
|---|---|---|
| XBI × | +26.57% | +65.22% |
|
Current
Drawdown |
Worst
Drawdown |
|
|---|---|---|
| XBI × |
−10.80%
on 2026-09-16 from 2021-02-08 peak |
−63.89%
on 2022-05-11 from 2021-02-08 peak |
| Period ending Wed 2026-09-16 | 1 yr | 2 yr | 3 yr | 5 yr | 10 yr |
|---|---|---|---|---|---|
| XBI × | +65.22% |
+52.97% +23.68%/yr |
+101.20% +26.24%/yr |
+18.44% +3.44%/yr |
+141.59% +9.22%/yr |
| Year | XBI |
|---|---|
| 2026 (YTD) | +26.57% |
| 2025 | +35.89% |
| 2024 | +1.01% |
| 2023 | +7.60% |
| 2022 | −25.87% |
| 2021 | −20.45% |
| 2020 | +48.33% |
| 2019 | +32.56% |
| 2018 | −15.28% |
| 2017 | +43.77% |
| 2016 | −15.45% |
| 2015 | +13.58% |
| 2014 | +44.97% |
| 2013 | +48.39% |
| 2012 | +32.69% |
| 2011 | +5.26% |
| 2010 | +17.60% |
| 2009 | +0.35% |
| 2008 | −8.57% |
| 2007 | +29.03% |
| 2006 | −6.31% |
