All charts and data below are with dividends reinvested. (Inflation adjustment is OFF !)

Total Real Returns

XBI: Total Return Chart (with Dividends Reinvested)

XBI total return snapshot: XBI returned +69.08% over the past year and +7.18% YTD, with dividends reinvested. Since Feb. 6, 2006, XBI is up +741.57% in nominal total return, or +11.08%/yr, and is currently āˆ’24.46% below its total-return high on Feb. 8, 2021.

Mon 2006-02-06? to Fri 2026-05-15 YTD
Return
1 Year
Return
XBI
×
+7.18%
2026-05-15
+69.08%
2026-05-15
SPDR S&P Biotech ETF Exchange-Traded Fund

Returns

Mon 2006-02-06? to Fri 2026-05-15 Overall
Return
Exponential
Trendline
XBI
×
+741.57%
+11.08%/yr
+12.40%/yr
(R2=0.851)
SPDR S&P Biotech ETF Exchange-Traded Fund

Growth of $10,000

Mon 2006-02-06? to Fri 2026-05-15 Start
Value
End
Value
XBI
×
$10,000.00
2006-02-06
$84,156.50
2026-05-15
SPDR S&P Biotech ETF Exchange-Traded Fund

Annual Returns

Year XBI
2026 (YTD) +7.18%
2025 +35.89%
2024 +1.01%
2023 +7.60%
2022 āˆ’25.87%
2021 āˆ’20.45%
2020 +48.33%
2019 +32.56%
2018 āˆ’15.28%
2017 +43.77%
2016 āˆ’15.45%
2015 +13.58%
2014 +44.97%
2013 +48.39%
2012 +32.69%
2011 +5.26%
2010 +17.60%
2009 +0.35%
2008 āˆ’8.57%
2007 +29.03%
2006 āˆ’6.31%

Drawdowns

Mon 2006-02-06? to Fri 2026-05-15 Current
Drawdown
Worst
Drawdown
XBI
×
āˆ’24.46%
from 2021-02-08 peak
āˆ’63.89%
2022-05-11
from 2021-02-08 peak
SPDR S&P Biotech ETF Exchange-Traded Fund

Rolling Returns

Period ending Fri 2026-05-15 1
Year
2
Years
3
Years
5
Years
10
Years
XBI
×
+69.08% +41.85%
+19.11%/yr
+50.08%
+14.49%/yr
+3.52%
+0.69%/yr
+162.82%
+10.14%/yr
SPDR S&P Biotech ETF Exchange-Traded Fund